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Ask QuestionPosted by Bharti Jain 6 years, 6 months ago
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Yogita Ingle 6 years, 6 months ago
Insulin from an animal source, though it caused some patients to develop allergy or other types of reactions to the foreign protein. Insulin consists of two short polypeptide chains : chain a and chain b, which are linked together by disulphide bridges. In mammals, including humans, insulin is synthesized as a pro-hormone, which contains an extra stretch called the C-peptide.
Posted by Bharti Jain 6 years, 6 months ago
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Posted by Bharti Jain 6 years, 6 months ago
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Yogita Ingle 6 years, 6 months ago
Eli Lilly prepared two DNA sequences corresponding to A and B chains of human insulin and introduced them in plasmids of <i>E.coli</i> to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin. Insulin in human pancreas is synthesised as a pro-hormone containing the C peptide, which is removed in mature hormone. The insulin synthesised by recombinant DNA technology did not contain C peptide and was prepared in the mature form.
Posted by Bharti Jain 6 years, 6 months ago
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Arif Ansari 6 years, 6 months ago
Yogita Ingle 6 years, 6 months ago
“Bipolarity” in international politics describes distribution of power between two states which exercise majority of economic, military and cultural influence internationally. There was bipolarity during the Cold War as the world had only two big super powers- former Russia and the USA.
Posted by Aa S 6 years, 6 months ago
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Yogita Ingle 6 years, 6 months ago
“Bipolarity” in international politics describes distribution of power between two states which exercise majority of economic, military and cultural influence internationally. There was bipolarity during the Cold War as the world had only two big super powers- former Russia and the USA.
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Kajal Sindhu 6 years, 6 months ago
2Thank You