Give some of the important change …

From the middle to the end of the 14th century, Europe was struck with the devastating pandemic of the Black Death — the bubonic plague — which in the short span of 1348–1350 wiped out fully one-third of the population. ... The plague continued to recur, though not in such virulent form, in every decade of the century. In Europe, the 15th century is seen as the bridge between the Late Middle Ages, the Early Renaissance, and the early modern period. ... The division of the Catholic Church and the unrest associated with the Hussite movement would become factors in the rise of the Protestant Reformation in the following century.

15th Century 1400-1499 CE

• Portugal extended its international trading routes. In Portugal navigation, exploration and mastery of the oceans dominated. ...
• The Hundred Years War continues. The costly war continues: ...
• The Renaissance gains momentum in Italy. ...
• The church in the 15th century. ...
• Gutenberg built a printing press in 1439.