Common features of prion
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Meghna Thapar 4 years, 5 months ago
Prions are best known as the infectious agents associated with prion diseases, the hallmark pathological features of which are the spongiform degeneration in the brain, accompanied by extensive neuronal loss, astrogliosis, and cerebral accumulation of the misfolded and protease-resistant form of prion protein. Prions are so small that they are even smaller than viruses and can only be seen through an electron microscope when they have aggregated and formed a cluster. Prions are also unique in that they do not contain nucleic acid, unlike bacteria, fungi, viruses and other pathogens.
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