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Yogita Ingle 5 years, 10 months ago
During skeletal muscle contraction, the thick filament slides over the thin filament by a repeated binding and releases of myosin head along the filament. This whole process occurs in a sequential manner.
Step 1: Muscle contraction is initiated by signals that travel along the axon and reach the neuromuscular junction or motor end plate. Neuromuscular junction is a junction between a neuron and the sarcolemma of the muscle fibre. As a result, Acetylcholine (a neurotransmitter) is released into the synaptic cleft by generating an action potential in sarcolemma.
Step 2: The generation of this action potential releases calcium ions from the sarcoplasmic reticulum in the sarcoplasm.
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