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Although O2 does not participate directly …

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Although O2 does not participate directly in TCA cycle the cycle operates only when O present, why??
  • 1 answers

Ajitha Reghu 4 years, 7 months ago

Although O2 is not needed in TCA CYCLE but it stops in the absence of O2 because it runs out ofNAD and FAD and O2 is final acceptor of electron in ETC . Without oxygen it stops and NAD cannot be produced thereby causing glycolysis to produce lactic acid instead of pyruvic acid which is a necessary component of TCA cycle .thus kreb cycle is heavily dependent on O2 for its aerobic process
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