Explain the five important step of …

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Posted by Nitin Dhakad 6 years, 9 months ago
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Yogita Ingle 6 years, 9 months ago
The important steps muscle contraction:
1. Muscle contraction is initiated by a signal sent by the central nervous system (CNS) via a motor neuron and reach the neuromuscular junction. As a result, neurotransmitter (Acetyl choline) which generates an action potential in the sarcolemma.
2. This spreads through the muscle fibre and causes the release of calcium ions into the sarcoplasm.
3. Increase in Calcium level leads to the binding of calcium with a subunit of troponin on actin filaments and thereby remove the masking of active sites for myosin. Utilising the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge.
4. The actin filaments are pulled. As a result, the H-zone reduces. It is at this stage that the contraction of the muscle occurs.
5. After muscle contraction, the myosin head pulls the actin filament and releases ADP along with inorganic phosphate. ATP molecules bind and detach myosin and the cross bridges are broken and decreases the calcium ions contraction. As a result, masking the actin filaments and leading to muscle relaxation.
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