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Posted by Lavanya ❤️? 5 years, 8 months ago
- 4 answers
Yogita Ingle 6 years, 9 months ago
A prions is an infectious agent composed of protein in a misfolded form. Prions propagate by transmitting a misfolded protein amyloid fold, in which the protein polymerises into an aggregate consisting of tightly packed state. When a prion enters a healthy organism, it induces existing, properly folded proteins to convert into the disease-associated, prion form; the prion acts as a template to guide the misfolding of more proteins into prion form. These newly formed prions can then go on to convert more proteins themselves; this triggers a chain reaction that produces large amounts of the prion form. All known prions induce the formation of an beta sheets. Amyloid aggregates are fibrils, growing at their ends, and replicating when breakage causes two growing ends to become four growing ends. The
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Lavanya ❤️? 6 years, 9 months ago
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