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Define RFLP

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Define RFLP
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Meghna Thapar 4 years, 3 months ago

Restriction fragment length polymorphism (RFLP) is a type of polymorphism that results from variation in the DNA sequence recognized by restriction enzymes. These are bacterial enzymes used by scientists to cut DNA molecules at known locations. Typically, gel electrophoresis is used to visualize RFLPs. RFLP is one of the earliest molecular markers developed for genetic mapping. The principle of RFLP markers is that any genomic DNA can be differentiated according to the presence or absence of restriction enzyme sites. Restriction enzymes recognize and cut at the particular site.

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