Difference between potipotency and pleuripotency
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Sia ? 4 years, 6 months ago
Totipotent
Pluripotent
Relative potency
High
Medium
Cell types capable of generating
Differentiate into any cell type
Differentiate into cells from any of the three germ layers
Terminology
Toti = Whole
Pluri = Many
Examples
Zygote, early morula
Embryonic stem cells, Induced pluripotent stem cells
Found
Early cells of fertilised egg
Inner mass cells of the blastocyst
Expression of pluripotency genes
+++
++
Expression of lineage-specific genes
+
++
Pros of use in research
Easy to isolate and grow
Easy to isolate and grow
Cons of use in research
Ethical issues
Ethical issues, teratoma formation
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