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Explain replicating fork.

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Explain replicating fork.
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Gaurav Seth 4 years, 9 months ago

 

DNA replication is the biological process in which two identical copies of DNA are produced from one original DNA molecule.
The steps involved in the process of DNA replication are as follows:

  1. The first step in DNA replication is to ‘unzip’ the double-helix structure of the DNA molecule.
  2. This is carried out by an enzyme called helicase which breaks the hydrogen bonds holding the complementary bases of DNA together (A with T, C with G).
  3. The separation of the two single strands of DNA creates a ‘Y’ shape called a replication ‘fork’. The two separated strands will act as templates for making the new strands of DNA.
  4. One of the strands is oriented in the 3’ to 5’ direction (towards the replication fork), this is the leading strand. The other strand is oriented in the 5’ to 3’ direction (away from the replication fork), this is the lagging strand. As a result of their different orientations, the two strands are replicated differently.
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