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Why DNA is stable and RNA …

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Why DNA is stable and RNA is in stable
  • 2 answers

Tanya ?? 4 years, 10 months ago

DNA is more chemically stable than RNA because it lacks the hydroxyl group on the 2' carbon. In RNA there are two possible OH groups that the molecule can form a phosphodiester bond between, which means that RNA is not forced into the same rigid structure as its deoxy counterpart.

Gaurav Seth 4 years, 10 months ago

Like DNA, RNA (ribonucleic acid) is essential for all known forms of life. RNA monomers are also nucleotides. Unlike DNA, RNA in biological cells is predominantly a single-stranded molecule. While DNA contains deoxyribose, RNA contains ribose, characterised by the presence of the 2'-hydroxyl group on the pentose ring. This hydroxyl group make RNA less stable than DNA because it is more susceptible to hydrolysis. RNA contains the unmethylated form of the base thymine called uracil.

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