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Mendallian disorders

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Mendallian disorders
  • 1 answers

Yogita Ingle 4 years, 11 months ago

  • Autosomal disorders – cystic fibrosis, sickle cell anaemia, myotonic dystrophy
  • ***-linked – haemophilia, colour blindness
  • HAEMOPHILIA – ***-linked recessive disease
  • A single protein that is a part of the cascade of proteins involved in the clotting of blood is affected.
  • In affected individual, a simple cut will result in non-stop bleeding.
  • Heterozygous female (carrier) can transmit the disease to son.
  • Possibility of female becoming a haemophilic is extremely rare.

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