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Mechanism of gene expression

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Mechanism of gene expression
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Gaurav Seth 5 years, 2 months ago

Gene expression in prokaryotes

Gene expression refers to the molecular mechanism by which a gene expresses a phenotype by synthesizing a protein or an enzyme. Which determines the character. The gene contains the blue print or the information for the protein or an enzyme.

The category includes mechanism involved in the rapid turn-on and turn-off gene expression in response to environmental changes. Regulatory mechanism of this type are very important in microorganisms, because of the frequent exposure of these organisms to sudden changes in environment.

Gene concept can be studied by operon model. Operon are segment of genetic material which function as regulated unit that can be switched on and switched off, which was given by French scientists. Jacob and Monod (1961) working at Pasteur institute. They were studying lactose utilization in mutants of E.coli. An operon consists of one to several structural genes (three in lac operon and five in tryptophan operon of Escherichia coli, nine in histidine operon of Salmonella typhimurium), an operator gene a promoter gene a regulator gene, a repressor and inducer or corepressor.

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