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What are chromosomal disorders?

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What are chromosomal disorders?

Posted by Nisha Yadav 5 years, 3 months ago

CBSE > Class 12 > Biology

1 answers

Yogita Ingle 5 years, 3 months ago

It is caused due to absence or excess or abnormal arrangement of one or more chromosomes.
Aneuploidy – failure of segregation of chromatids during cell division cycle results in the gain or loss of chromosome.
Polyploidy – Failure of cytokinesis after telophase stage of cell division results in an increase in a whole set of chromosomes in an organism.
Down’s syndrome – gain of extra copy of chromosome 21 (trisomy 21)
It was first described by Langdon Down (1866).
Affected individual is short with small round head, furrowed tongue and partially open mouth.
Broad palm with characteristic palm crease.
Physical, psychomotor and mental development is retarded.

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