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Why sickel cell anemia is called …

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Why sickel cell anemia is called mandelian disorder ?
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Disorders explained by mendel laws called mendelian disorders.

Gaurav Seth 6 years ago

Sickle-cell anaemia is a blood related autosomal Mendelian disorder. It is an autosomal recessive genetic disorder. The disease is caused by a mutation in the beta-globin gene responsible for producing a subunit of haemoglobin. It is called Mendelian disorder because it is controlled by a single locus in an inheritance pattern and mutation in a single gene can cause a disease. Since it is a recessive disorder, two defected genes must be transferred from parents to offsprings in order to have the disease. When only one defective gene is transferred from the parent to offspriing, it results in the sickle cell trait. In this, the offspring is carrier of the diseas

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