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Explain the mechanism of translation that …

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Explain the mechanism of translation that occures in the ribosome in a prokaryote
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Meghna Thapar 5 years, 8 months ago

  • Translation involves translating the sequence of a messenger RNA  (mRNA) molecule to a sequence of amino acids during protein synthesis.
  • It is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA.

    Each prokaryotic ribosome, shown schematically, has three binding sites for tRNAs.

  • The aminoacyl-tRNA binding site (or A site) is where, during elongation, the incoming aminoacyl-tRNA binds.
  • The peptidyl-tRNA binding site (or P site) is where the tRNA linked to the growing polypeptide chain is bound.
  • The exit site (or E site) is a binding site for tRNA following its role in translation and prior to its release from the ribosome.
  • All three sites (A, P and E) are formed by the rRNA molecules in the ribosome.

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