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What is lackperon??????

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What is lackperon??????
  • 2 answers

Aarushi Singh 6 years, 3 months ago

An operon required for transport and metabolism of lactose in E.coli or other bacteria is called Lactose operon

Yogita Ingle 6 years, 3 months ago

  • Lac refers to lactose in lac operon.
  • The lac operon consists of one regulatory gene the i gene which codes for the repressor of the lac operon and three structural genes (z, y, and a).
  • The z gene codes for beta-galactosidase (β-gal), which hydrolyses disaccharide, lactose into galactose and glucose.
  • The y gene codes for permease, which increases permeability of the cell to β-galactosides.
  • The a gene encodes a transacetylase.
  • Lactose is termed as inducer as lactose is the substrate for the enzyme beta-galactosidase and it regulates switching on and off of the operon.
  • In the absence of inducer
  • The repressor of the operon is synthesized (all-the-time – constitutively) from the i gene.
  • The repressor protein binds to the operator region of the operon and prevents RNA polymerase from transcribing the operon.
  • In the presence of inducer
  • The repressor is inactivated by interaction with the inducer which allows RNA polymerase access to the promoter and transcription proceeds.
  • Regulation of lac operon by repressor is referred to as negative regulation.
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