Difference between haemophilia and thalassemia

Definition

Hemophilia

Is an inherited bleeding disorder, manifesting predominantly in worldwide male population. However, about 30% of hemophilia patients have no prior family history of bleeding disorder. In these cases, it is caused by mutation in their genes that lead to bleeding disorder. It is a lifelong disease.

Thalassemia

Is a group of inherited blood disorders. It can affect people of any nationality, but it is particularly common in people with ancestry from the Mediterranean and across a broad region extending through India, the Middle East and Asia. It can occur in both male and female population. It is a lifelong disease.

Root Cause

Hemophilia

People with hemophilia have either defective or lack of clotting factors. Clotting factors are protein in blood necessary to stop bleeding. The body produces 13 clotting factors. If any of them are defective or deficient, blood clotting is affected. People with hemophilia usually have longer bleeding time compared to unaffected people.

Thalassemia

People with thalassemia have either abnormal or lack of hemoglobin in their red blood cells. The bone marrow is responsible for the production of hemoglobin, using iron from diet intake to produce hemoglobin.