Differentiate between sickle cell anaemia and …

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Differentiate between sickle cell anaemia and thalassemia in tabular form .

Posted by Deepika Gaur 6 years, 6 months ago

CBSE > Class 12 > Biology

1 answers

Hy Shona 6 years, 6 months ago

Sickel cell anaemia-1)this defect is caused by the substitution of Glutamic acid by valine at the 6th position of yhe beta globin chain of the haemoglobin molecule . 2)the mutant haemoglobin molecule suffers from low oxygen tension causing the change in the shape of the RBC from biconcave disc to elongated sickle like structure . Thalassemia-1)this defect arises due to mutation or deletion which ultimately results in reduced rate of synthesis of one of the globin chain that make up the haemoglobin. THALSSEMIA is the quantitive problem of synthesising too few globin molecule while the SICKLE-CELL ANAEMIA is the qualitative problem of synthesising an incorrectly functioning globin.

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