Definition for soluble and sink
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Meghna Thapar 5 years, 5 months ago
Sink condition is the ability of the dissolution media to dissolve at least 3 times the amount of drug that is in your dosage form. Having sink conditions helps your dissolution have more robustness as well as being more biologically relevant. One of the requirements to conduct an appropriate drug dissolution test is to use a sufficient volume of dissolution medium, which should be able to dissolve the expected amount of drug released from a product. This ability of the medium to dissolve the expected amount of drug is known as a “sink condition”.
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