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Describe the post transcriptional modification in …

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Describe the post transcriptional modification in eukaryotic and mRNA
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Yogita Ingle 3 years, 6 months ago

Post transcriptional modification of hnRNA in eukaryotes includes three event. Splicing is removal of introns from the primary transcript and ligation of exons to form a continuous sequence specifying a functional polypeptide. Capping of eukaryotic mRNAs refers to addition of 7-Methylguanosine to the 5’ end of almost all eukaryotic mRNAs in an unusual 5’,5’- triphosphate linkage. Tailing refers to cleavage of 3’ end and addition of 80 to 250 A residues to create a poly(A) tail.

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