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Posted by Srinivas Chandra 6 years, 10 months ago
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Payal Singh 6 years, 10 months ago
Kolbe's reaction: When phenol is treated with sodium hydroxide, sodium phenoxide is produced. This sodium phenoxide when treated with carbon dioxide, followed by acidification, undergoes electrophilic substitution to give ortho-hydroxybenzoic acid as the main product.
This reaction is known as Kolbe's reaction.
Williamson ether synthesis: Williamson ether synthesis is a laboratory method to prepare symmetrical and unsymmetrical ethers by allowing alkyl halides to react with sodium alkoxides.
This reaction involves SN2 attack of the alkoxide ion on the alkyl halide. Better results are obtained in case of primary alkyl halides.
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